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1페이지
colon/distal cut margin/paraaortic LN LN/IMV LN LN/252 L
N/25.g LN/253 LN ICG(+)
(GROSS DESCRIPTIONI
Submitted specimen: Rectum with seoarate lymph nodes
Specimen type: low anterior resection
size: 14.5 cm in length. distal Cut margin: one. 4.7 0.8 x 0.4 cm
Tumor type: fungating
Tumor site: rectum
Tumor size: 1.6 x 1.4 x 0.7 cm
Resection margin: proximal: 12.0 cm. dstal: 2.2 cm. mesenteric: 3.0 cm
[MICROSCOPIC DESCRIPTION]
—Location: rectum
-Size: 1.6 x 1.4 x 0.7 cm
—Deoth Of invasion: invades submucosa (sm3) (pT1). (depth Of sm invasion: 3 mm)
—Resection (proximal & distal) margin involvement: absent
safety margin: proximal 12.0 cm. distal 2.2 cm. mesenteric 3.0 cm. circumferential 2.0 cm
—Pattern ot tumor growth: expanding
-Lymphatic invasion: present
-Venous invasion: absent
—Perineural invasion: absent
—Lypoh node metastasis: absent (0/29) (pN0)
— regional LW 0/20
paraaortic LN ICG(+): 0/2
- IMV LN: 0/0
- IMV LN CG(+): 0/2
- 242 LN: 0/1
- 252 LN; 0/1
- 25a LN: 0/0
- 253 LN ICG(+): 0/3
—Pre-existing adenoma: tubular adenoma. low grade dysplasia
size: 1.6 x 1.4 x 0.7 Crn
-Separate lesion: absent
[DIAGNOSIS]
Rectum. low anterior resection:
Adenocarcinoma moderately differentiated
[CFI
WI-004932. WI-004933. '*21-004934. QI-013225
2페이지
Verhoeff-Van Gieson Elastic
[SPECIAL STAINING RESULT]
HS21-001442 Elastic absence ot vascular invasion
3페이지
EGFR
[IMMUNOHISTOCHEMISTRY]
H21-003852 EGFR positive (1+)
4페이지
KRAS exon 2.3.4 PNAClamp
[MOLECULAR PATHOLOGY]
M21-004933 KRAS exon 2.3.4 PNAClamp
[Result]
검사벙법
PNA—mediated real—time PCR (PNACLarnpTU KRAS Mutation Detection Kit Ver.4)
검사결과
KAAS codon 12. 13. 59. 61. 117. 146
Mutation : Negative - codon 146 mutant
5페이지
NRAS PNA Clamp
[MOLECULAR PATHOLOGY]
M21-004932
NRAS PNA Clamp
Sample adequacy
Adequate
Result
PNA—mediated real-time PCR (PNAClarno'U NRAS Mutation Detection Kit)
검사결과
Mutation : Negative
6페이지
MSI test
[MOLECULAR PATHOLCGY]
M21-004934 MSI
SDample adequacy
Adequate (Normal : 1-1. Tumor : 1—8)
Result
Melting Array-mediated multiplex real-time PCR (U—TOP)
검사결과
MSI (microsatellite instability)
MSS (microsatellite stable)
BAT-26 Negative
NR-24 Negative
NR-21 Negative
NR-27 Negative
BAT-25 Negatrve
7페이지
Level C
[GROSS DESCRIPTION]
Number ot 1) Three. 2) Two. 3) One. Three
Specimen size: 1) up to 0.2 x 0.2 cm. 2) up to 0.5 0.2 cm. 3) 0.5 x 0.1 cm. 4) up to 0.2 x 0.2 cm
(Block 4)
[DIAGNOSIS]
. Colon. descending. snare
Tubular adenoma with low grade dysplasia.
•resection margin invowernent: cannot be assessed
2. Colon. descending. snare
Tubular adenoma with bw grade dyseasia.
•resection margin involvement: cannot assessed
3. Colon. sigmoid. snare ootycmztomy(C2):
Tubular adenoma with low grade dysolasia.
•resection margin involvement: cannot be assessed
4. Rectum. endoscopic bioosy(C4):
Tubular adenoma With low grade dysplasia.