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GROSS:
1. Specimen status: Fresh
2. Operation: Partial mastectomy
3. Specimens:
No.1) Labeled as "left breast (10/I &4)" is a lump of breast, 3.0x1.8x1. Ocm and 5.80m with attached two suture tagging with wire
4. Lesion:
No.2) Labeled as "left breast (12\| gt)" is a lump of breast, 3.5×2.4%1. 0cm with attached two suture marking and wire hooking No. 1 : Serial sections no definite mass
No.2 : No definite mass lesion
5. Ink code: deep- black, superior- red, inferior - blue
6. Slide keys: 17 cassettes (entirely embedded after serial section (mapping))
(No.1 : No. 1-7, No.2 : No.8-17)
(17HE, 1ER, 1PR, 1HER2, 1Ki-67, 1bc-2, 3CK5/6, 1EGFR, 1p63)
MICROSCOPIC FINDING :
[Immunohistochemical stain : No. 17]
1. Estrogen receptor : Positive reaction
- intensity : strong
- proportion : ≥67%
2. Progesterone receptor: Positive reaction
- intensity : intermediate
- proportion: ≥67%
3. HER-2/neu: Equivocal reaction (2)
4. Ki-67 labeling index : 2.2%
5. bc-2 : Positive reaction (90%)
6. Epidermal growth factor receptor: Negative reaction
7. Cytokeratin 5/6 : Negative reaction
8. 063 : Negative reaction
DIAGNOSIS:
Breast, left 12 o'clock, partial mastectomy
- Ductal carcinoma in situ, intermediate grade (pTis)
- non-high nuclear grade
- focal necrosis and calcification
with 1) undetermined (involved or close) medial resection margin*
2) close deep resection margin (0. 1cm in distance)
Breast, left 10 o'clock, partial mastectomy
1. Usual ducal hyperplasia
2. Adenosis
3. Fibrocystic change with microcalcification